|
KMID : 0882420110810040512
|
|
Korean Journal of Medicine
2011 Volume.81 No. 4 p.512 ~ p.516
|
|
|
A Case of Combining Intravenous Immunoglobulin and Leflunomide for BK Nephropathy
|
|
Cho Sun-Young
Bae Jeong-Mo
Nam Woo-Jin
Kim Jin-Gun
Kim Su-Hyun
Oh Dong-Jin
Yu Suk-Hee
|
|
|
Abstract
|
|
|
|
BK virus nephropathy has emerged as an important cause of renal allograft dysfunction. It affects 1-10% of renal transplant patients and results in significant graft dysfunction in more than 50% of cases. A reduction in the amount of immunosuppressants is not an appropriate treatment option for advanced stage BK nephropathy; therefore, other treatment strategies need to be considered such as cidofovir, leflunomide, and intravenous immunoglobulin (IVIG) in combination with reduced immunosuppression. The use of IVIG may be a valuable treatment option in patients with BK virus nephropathy. We report our experience with IVIG rescue therapy in a patient and the progression of BK nephropathy despite leflunomide therapy.
|
|
|
KEYWORD
|
|
|
BK virus, Immunoglobulin, Kidney transplantation, Leflunomide
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|